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目的 对老年髋部骨折患者衰弱的发生率及影响因素进行系统性评价，为早期识别高危人群、进行针对性的干预措施提供依据。方法 计算机检索中国知网、万方、维普、中国生物医学文献数据库、Pubmed、Embase、Web of Science、The Cocrone Library数据库中与老年髋部骨折患者衰弱相关的观察性研究，检索时限为建库至2025年2月28日。由2名研究者独立进行文献筛选和质量评价，采用Stata17.0软件进行Meta分析。结果 共纳入25篇研究。Meta分析结果显示：老年髋部骨折患者衰弱发生率为34%。BMI和血红蛋白为老年髋部骨折患者衰弱的保护因素；年龄、性别、查尔森合并症指数（CCI）、从不锻炼、骨质疏松、近1年有跌倒史、抑郁、认知障碍、基础疾病多、多重用药、肌酐、术后长时间卧床、贫血、营养不良、独居、缺乏家庭关怀是老年髋部骨折患者衰弱的危险因素（P均<0.05）。结论 老年髋部骨折患者受身体因素、疾病及相关因素和其他因素的影响，衰弱的发生率较高。
Abstract：Objective To conduct a systematic review on the incidence of frailty and its influencing factors in elderly patients with hip fracture, and to provide evidence for early identification of frailty high risk group and implementation of individualized intervention measures. Methods Observational studies related to frailty in elderly patients with hip fracture were retrieved from databases including CNKI, Wanfang, VIP, CBM, Pubmed, Embase, Web of Science, and The Cocrone Library via computer-based search. The search was restricted to the period from the databases' establishment up to February 28, 2025. Literature screening and quality evaluation were performed by two investigators. Meta analysis was performed by Stata 17. 0 software. Results A total of 25 studies were included. The results of meta-analysis showed that the incidence of frailty in elderly patients with hip fracture was 34%. BMI and hemoglobin were protective factors for frailty in elderly patients with hip fracture; age, gender, CCI, never exercised, osteoporosis, history of falls in the past year, depression, cognitive impairment, multiple underlying disease, polypharmacy, creatinine, prolonged bed rest after operation, anemia, malnutrition, living alone, and lack of family care were the risk factors of frailty in elderly patients with hip fracture(all P<0. 05). Conclusion The incidence of frailty is relatively high in elderly patients with hip fracture, which is influenced by physical factors, disease-related factors, and other factors.
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基本信息:
DOI：
中图分类号:R683
引用信息:
[1]王庆,靳绮,袁艳玲,等.老年髋部骨折患者衰弱发生率及其影响因素的Meta分析[J].老年医学研究,2025,6(06):20-25.
基金信息: